The role of 1,2-epoxyindene in the metabolism of indene in vivo [proceedings].

low an efficiency. Our limited project also points to an insensitive relationship between plasma immunoreactive insulin of exogenous origin and biochemical hypoglycaemia. This agrees with Galloway & Root (1972) and so appears to be liposome-independent. Should diabetic subjects show similar response patterns, future investigations will have two principal directions: (a) human studies of liposomes densely charged with insulin and (6) efforts towards a rational improvement in the efficiency of the uptake and subsequent metabolic response. Economic and therapeutic advantages of the latter approach have already led us to experiments for determining factors that presently limit efficacy of the liposomal hormone.